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When other medications are not helpful in relieving pain, then the Codeine drug acts as an effective painkiller. The generic form and active ingredient are the same in this branded drug. It falls under the category of medications which is commonly known as opioid-based drugs. This Codeine 60 mg medication is a prodrug of morphine, which means the conversion from therapeutic inactive form to active medicinal product.
The Codeine drug helps to get relief from the pain which may emerge after severe injury, surgery, etc. It helps in reducing the unpleasant feeling of pain that may vary from mild to moderate chronic pain. It is white, round-shaped, and imprinted with initials of 99 on the tablet.
The use of this medicine for treating various pain is approved by the US FDA, and it is manufactured by Roxane Laboratories Inc. Due to its potential to be abused and misused by individuals, the Controlled Substance Act classified this product as a Schedule II controlled substance.
Codeine 60 mg has the properties of an opioid agonist. It has a high tendency to combine with the mu-opioid receptor or MOR (G-protein). The affinity of morphine for MOR is more than Codeine.
It activates the G-proteins and as a result, the concentration of cAMP (cyclic Adenosine Monophosphate) and Calcium level gets decreased.
As a result, the membrane of the cell becomes negative, which causes hyperpolarization of the neuron. The glutamate is released by the excitatory neurons, which decreases the neuronal excitability. All this mechanism helps in producing analgesic effects to reduce pain in an individual.
It comes in the form of an oral tablet with the following dosage strengths; 15 mg, 30 mg, and 60 mg. The nominal dose is 15 mg and the dose can be increased up to 60 mg or else it is decided by a doctor.
The administration of dose and dosage strength is recommended by a healthcare expert. The dose for adults is different for children. The dosage strength mostly depends on the patient’s age and the severity of the pain.
It is a prodrug of morphine, and it has various uses, which are given below:-
This medicine is approved to treat various pain, which may vary from mild to moderate (severe) pain in adults.
Off-label this drug is used to treat various health problems, these are mentioned below:-
The individuals who are experiencing cough can be treated with the help of the drug.
It is a bowel disease in which there is a frequency of watery stool quite often.
It is a movement condition in which there is the urge to move legs. Usually, it occurs in the evening.
The dosage strength is 60 mg of Codeine has common and severe side effects as follows-
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